Premature ovarian Insufficiency (failure)
What is meant by premature ovarian Insufficiency (failure)?
It is the decline and loss of ovarian reserve before the age of 40
What are the causes of premature ovarian Insufficiency?
** Genetic factors that lead to accelerated consumption of ovarian reserve, which leads to its expiration before the expected time
** Chromosomal disorders such as Turner syndrome
** Surgical procedures (removal of part of the ovary or removal of the entire ovary)
** Chemotherapy or radiation treatments
** Smoking
What are the complications resulting from premature ovarian Insufficiency?
Loss of the female hormone secreted by the ovary, which results in:
**Lack of sexual desire
**Vaginal dryness
**Urinary incontinence
**Recurrent female infections
**Hot flashes
**Osteoporosis
**High blood lipids
**Increased incidence of cardiovascular diseases
Can premature ovarian Insufficiency be avoided?
This depends on the cause:
** If it is due to genetic/chromosomal factors, it cannot be avoided.
** If it is due to surgical procedures, it is possible to try as much as possible during ovarian surgeries to preserve as much of its cortex as possible.
** In cases of chemotherapy/radiation therapy, it is possible to freeze part of the ovarian cortex and replant it after the end of the treatment period, and we may resort to freezing eggs to preserve reproductive capacity.
** Stop smoking and shisha.
How is early ovarian Insufficiency treated?
This depends on the cause, the woman's reproductive desire, and the symptoms she complains of:
** Hormone replacement therapy (hormonal pills containing the female hormone) to avoid complications resulting from a deficiency of this hormone
** Freezing eggs/ovarian cortex in certain cases to preserve reproductive capacity
**Some people in some countries may resort to donating eggs for the purpose of reproduction
**Ovarian plasma, but its results are not guaranteed and do not exceed 1 percent
**Stem cell technology, which is still under study and has not been proven effective in humans