I.V.M
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What is IVM treatment?
IVM stands for In Vitro Maturation. 'In vitro' comes from the Latin meaning 'in glass' and 'maturation' is the process of aging something from infancy to maturity. In IVM, immature eggs, or oocytes, are retrieved from the ovary, then matured in the laboratory before being fertilised and replaced to the womb.
What is the procedure for IVM?
IVM is much easier than conventional treatment and requires much less time commitment. 1. Under the guidance of ultrasound, the immature eggs are retrieved from a woman's unstimulated ovaries. 2. The eggs are then matured in the laboratory for 24-48 hours. 3. The eggs that have matured after this time are fertilised using traditional techniques such as ICSI. 4. Two to three days after fertilisation, the embryos are transferred to the mother's womb.
How does it differ from IVF?
There are two main differences between IVM and IVF and they are safety and cost. In standard IVF treatment the woman undergoes 2 weeks of injections to stimulate egg production prior to retrieval. As well as being time-consuming and uncomfortable, a potentially fatal side-effect of these injections is a condition known as Ovarian Hyperstimulation Syndrome (OHSS). IVM does not need these daily injections so there is no risk of OHSS. And because the treatment is shorter than IVF, there is no need for women to have to sniff an ovary suppressing drug for 2-3 weeks prior to injections. Mr Tim Child, Consultant Gynaecologist at the Oxford Fertility Clinic, says as well as being easier, IVM will be less expensive than traditional IVF treatment. "The cost of drugs, which is often largely met by the patients, is reduced, meaning IVM has the potential to become a more accessible form of fertility treatment."
Who is it suitable for?
To begin with, the Oxford Fertility Unit is only offering IVM to women with polycystic ovaries. However, it is thought the procedure will be ideally suited to women below their mid thirties as an alternative to IVF.
What are the success rates?
So far, over 400 babies have been born worldwide through IVM treatment and Danish scientists have achieved 30 per cent success rates using the procedure. Professor Bob Edwards, who helped create the world's first IVF baby, Louise Brown, believes that IVM could be safely used to treat most women with fertility problems and will revolutionise fertility treatments. "I see IVM as an all-round - and cheaper - solution," he says. "This really is a new era for IVF. A revolution. I think IVM will replace IVF. It all looks very promising."